The Knowledge-Triangle Platform for the Water-Energy-Food Nexus (TriNex) is a multidisciplinary project aimed at addressing the deep-rooted research and innovation vacuum in Egypt. With its emphasis on the importance of the Water-Energy-Food (WEF) Nexus as the launching pad for Egypt’s development, it will provide a unique and vital boost to Egypt’s ailing research establishment with particular focus on Egypt’s looming security difficulties. Through the TriNex Project, a much needed injection of essential research and innovation will be provided to Egypt.